Publications

  1. Monfort-Pires M, U-Din M, de Mello V, Saari T, Raiko J, Kerminen E, Rajander J, Hanhineva K, Fromme T, Landberg R, Klingenspor M, and Virtanen KA. (2025) Cold-induced serum short-chain fatty acids act as markers of brown adipose tissue metabolism in humans. The Journal of Clinical Endocrinology & Metabolism. dgaf607.
  2. Grein S, Elschner T, Kardinal R, Bruder J, Strohmeyer A, Gunasekaran K, Witt J, Hermannsdóttir H, Behrens J, U-Din M, Yu J, Heldmaier G, Schreiber R, Rozman J, Heine M, Scheja L, Worthmann A, Heeren J, Wachten D, Wilhelm-Jüngling K, Pfeife A, Hasenauer J, and Klingenspor M. (2025). Shiny-Calorie: A context-aware application for indirect calorimetry data analysis and visualization using R. Bioinformatics Advances. vbaf270.
  3. U-Din M, Ahmed BA, Syed SA, Ong FJ, Oreskovich SM, Gunn E, Surette MG, Punthakee Z, Steinberg GR, and Morrison KM. (2024). Characteristics of Abdominal Visceral Adipose Tissue, Metabolic Health and the Gut Microbiome in Adults. The Journal of Clinical Endocrinology and Metabolism. 109(3):680-690
  4. U-Din M, de Mello V, Tuomainen M, Raiko J, Niemi T, Fromme T, Klåvus A, Gautier N, Haimilahti K, Lehtonen M, Kristiansen K, Newman JW, Pietiläinen KH, Pihlajamäki J, Amri EZ, Klingenspor M, Nuutila P, Pirinen E, Hanhineva K, Virtanen KA. (2023) Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans. Cell Reports. 42(9):113131
  5. Pellegrinelli V, Figueroa-Juárez E, Samuelson I, U-Din M, Rodriguez-Fdez S, Virtue S, Leggat J, Çubuk C, Peirce VJ, Niemi T, Campbell M, Rodriguez-Cuenca S, Blázquez JD, Carobbio S, Virtanen KA, Vidal-Puig A. (2023) Defective extracellular matrix remodeling in brown adipose tissue is associated with fibro-inflammation and reduced diet-induced thermogenesis. Cell Reports. 42(6).
  6. Hachemi I, U-Din M. (2023) Brown Adipose Tissue: Activation and Metabolism in Humans. Endocrinology and Metabolism 38(2):214-222
  7. U-Din M, Rebelos E, Saari T, Niemi T, Kuellmer K, Eskola O, Fromme T, Rajander J, Taittonen M, Klingenspor M, Nuutila P, Nummenmaa L, Virtanen KA. (2023) Thermogenic Capacity of Human Supraclavicular Brown Fat and Cold-Stimulated Brain Glucose Metabolism. Metabolites 2023;13(3).
  8. Monfort-Pires M, Regeni-Silva G, Dadson P, Nogueira GA, U-Din M, Ferreira SRG, Sapienza MT, Virtanen KA, Velloso LA. Brown fat triglyceride content is associated with cardiovascular risk markers in adults from a tropical region. Front Endocrinol (Lausanne). 2022 Jul 19;13:919588.
  9. Saari, T., Koffert, J., Honka, H., Kauhanen, S., U-Din, M., Wierup, N., Lindqvist, A., Groop, L., Virtanen, K. A., & Nuutila, P. (2022). Obesity associated blunted subcutaneous adipose tissue blood flow after meal is improved after bariatric surgery. The Journal of Clinical Endocrinology and Metabolism. In press.
  10. Laurila, S., Rebelos, E., Lahesmaa, M., Sun, L., Schnabl, K., Peltomaa, T. M., Klén, R., U-Din, M., Honka, M. J., Eskola, O., Kirjavainen, A. K., Nummenmaa, L., Klingenspor, M., Virtanen, K. A., & Nuutila, P. (2022). Novel effects of the gastrointestinal hormone secretin on cardiac metabolism and renal function. American Journal of Physiology – Endocrinology and Metabolism, 322(1), E54.
  11. Schnabl K, Li Y, U-Din M, Klingenspor M. (2021) Secretin as a satiation whisperer with the potential to turn into an obesity-curbing knight. Endocrinology. 1;162(9):bqab113.
  12. Laurila S, Sun L, Lahesmaa M, Schnabl K, Laitinen K, Klén R, Li Y, Balaz M, Wolfrum C, Steiger K, Niemi T, Taittonen M, U-Din M, Välikangas T, Elo L, Eskola O, Kirjavainen A, Nummenmaa L, Virtanen KA, Klingenspor M, Nuutila P. (2021) Secretin Activates Brown Fat and Induces Satiation. Nature Metabolism. Accepted.
  13. Monfort-Pires M, U-Din M, Nogueira GA, Almeida-Faria J, Sidarta-Oliveira D, Sant’Ana MR, Lima-Júnior J, Cintra DE, Possolo de Souza H, Ferreira SRG, Sapienza MT, Virtanen KA, Velloso LA. (2020) Short dietary intervention with olive oil increases brown adipose tissue activity in lean but not overweight subjects. Journal of Clinical Endocrinology and Metabolism. 106(2):472-484.
  14. Saari TJ, Raiko J , U-Din M, Niemi T, Taittonen M, Laine J, Savisto N, Haaparanta-Solin M, Nuutila P,  Virtanen KA. (2020). Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity. Scientific Reports. 10(1):14373.
  15. Ojala R, Motiani KK, Ivaska KK, Arponen M, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Heiskanen MA, U-Din M, Nuutila P, Kalliokoski KK, Hannukainen JC. (2020). Bone marrow metabolism is impaired in insulin resistance and improves after exercise training. Journal of Clinical Endocrinology and Metabolism. 105(12):e4290-e4303.
  16. Li Y, Braun K, Gabler SM, Willershäuser M, Reber J, Karlas A, Laurila S, Lahesmaa M, U-Din M, Bast A, Virtanen KA, Fromme T, Bolze F, O’Farrell LS, Fernandez JA, Coskun T, Ntziachristos V, Nuutila P, Klingenspor M. (2018) Secretin-activated brown fat mediates prandial thermogenesis to induce satiation. Cell. 175(6):1561-1574.  
  17. U-Din M, Saari T, Raiko J, Kudomi N, Maurer FS, Lahesmaa M, Fromme T, Amri EZ, Klingenspor M, Solin O, Nuutila P, Virtanen KA. (2018) Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis. Cell Metabolism. 28(2): 207-216.   
  18. Dadson P, Hannukainen JC, U-Din M, Lahesmaa M, Kalliokoski KK, Iozzo P, Pihlajamäki J, Karlsson HK, Parkkola R, Salminen P, Virtanen KA, Nuutila P. (2018). Brown adipose tissue lipid metabolism in morbid obesity: Effect of bariatric surgery-induced weight loss. Diabetes Obesity Metabolism. 20(5):1280-1288.
  19. Lahesmaa M, Oikonen V, Helin S, Luoto P, U-Din M, Pfeifer A, Nuutila P, Virtanen KA. (2018) Regulation of human brown adipose tissue by adenosine and A2A receptors – studies with [15O]H2O and [11C]TMSX PET/CT. European Journal of Nuclear Medicine and Molecular Imaging. 46(3):743-750.
  20. Lahesmaa M, Eriksson O, Gnad T, Oikonen V, Bucci M, Hirvonen J, Koskensalo K, Teuho J, Niemi T, Taittonen M, Lahdenpohja S, U-Din M, Haaparanta-Solin M, Pfeifer A, Virtanen KA, Nuutila P. (2018) Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue. Diabetes. 67(7):1226-1236.
  21. Motiani P, Virtanen KA, Motiani KK, Eskelinen JJ, Middelbeek RJ, Goodyear LJ, Savolainen AM, Kemppainen J, Jensen J, U-Din M, Saunavaara V, Parkkola R, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC. (2017). Decreased insulin-stimulated brown adipose tissue glucose uptake after short-term exercise training in healthy middle aged men. Diabetes Obesity Metabolism. 19(10):1379-1388.
  22. U-Din M, Raiko J, Saari T, Saunavaara V, Kudomi N, Parkkola R, Nuutila P, Virtanen KA. (2017). Human Brown Fat Radiodensity Indicates Underlying Tissue Composition and Systemic Metabolic Health. Journal of Clinical Endocrinology and Metabolism. 102 (7): 2258-2267.  
  23. U-Din M, Raiko J, Saari T, Kudomi N, Tolvanen T, Oikonen V, Teuho J, Sipila HT, Savisto N, Parkkola R, Nuutila P, Virtanen KA. (2016). Human Brown Adipose Tissue [15O]O2 PET Imaging in the Presence and Absence of Cold Stimulus. European Journal of Nuclear Medicine and Molecular Imaging. 43: 1878-1886.
  24. Silvoniemi A, U-Din M, Suilamo S, Shepherd T, Minn H. (2016). Radiotherapy volume delineation using dynamic [18F]-FDG PET/CT imaging in patients with oropharyngeal cancer: a pilot study. International Journal of Computer Assisted Radiology and Surgery. 11, 2059–2069.
  25. Asghar MN, Emani R, Alam C, Helenius TO, Grönroos TJ, Sareila O, U-Din M, Holmdahl R, Hänninen A, Toivola DM. (2014). In vivo imaging of reactive oxygen and nitrogen species in murine colitis. Inflammatory Bowel Diseases. 20(8): 1435-47.
  26. U-Din M. Oxidative metabolism and non-invasive characterisation of brown adipose tissue in adult humans. (2018). Doctoral thesis, University of Turku, Turku, Finland. Permanent link: http://urn.fi/URN:ISBN:978-951-29-7220-3
  27. U-Din M. Differentiation of Metabolically Distinct Areas within Head and Neck Region using Dynamic 18F-FDG Positron Emission Tomography Imaging. (2013). Masters thesis. University of Turku, Turku, Finland. Permanent link: http://urn.fi/URN:NBN:fi-fe201401281303